Amino acid loss during hemodialysis between amino acid plus dextrose infusion and sequential dextrose and amino acid infusion: a randomized, crossover trial

Comparison of amino acid loss during hemodialysis between amino acid plus dextrose infusion and sequential dextrose and amino acid infusion: a randomized, crossover trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230317005

Enrollment

Registered

2023-03-17

Start date

2022-08-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnourished patients with chronic hemodialysis intradialytic parenteral nutrition, amino acid loss, hemodialysis

Interventions

Infusion of amino acid plus dextrose was begun at the exact onset of the dialysis procedure and was continued at a constant rate until the termination of the dialysis,Infusion of dextrose was begun a

Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery

Continuous amino acid plus dextrose infusion ,Sequential Dextrose/Amino acid infusion

Eligibility

Sex/Gender

All

Age

No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Age more than 20 years Chronic hemodialysis on 3per week Informed consent Indication for IDPN according to Clinical practice recommendation for Nutrition Management in Adult Kidney Patients 2018

Exclusion criteria

Exclusion criteria: Volume overload Sepsis Hypotension from cardiac cause Advanced malignancy Advanced liver disease Blood flow rate < 250 ml/min

Design outcomes

Primary

Measure	Time frame
Amino acid losses in dialysate 1 week Amino acid concentration by Chromatographic Condition	—

Secondary

Measure	Time frame
Changes in plasma amino acid concentrations 1 week Amino acid concentration by Chromatographic Condition	—

Countries

Thailand

Contacts

Public ContactSarinpa Uparimat

Phramongkutklao hospital

sarinpa555@gmail.com0885808005

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026