patients who diagnosed acute otitis externa age older than 18 years acute otitis externa thimerosal boric acid powder ofoxacin
Conditions
Interventions
ofloxacin 3 drop at affected ear for 7 days,thimerosal 3 drop at affected ear for 1-2 minutes then ear toilet and applied boric acid powder for 3-5 puff (single dose)
Active Comparator Drug,Experimental Drug
Ofloxacin group,thimerosal with boric acid powder
Sponsors
Department of Otolaryngology Faculty of Medicine Ramathibodi Hospital Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: patients who diagnosed acute otitis externa age older than 18 years
Exclusion criteria
Exclusion criteria: perforated tympanic membrane on the affected side dermatitis acute otitis media history of receiving antibiotic or steroid in the previous month malignant otitis externa severe acute otitis externa (CSS > 10) history of hypersensitivity reaction to thimerosal, boric acid powder, ofloxacin otic drop, or 10% xylocaine spray on immunosuppressant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in clinical symptom score between two groups at day 3, 7 and 14 post treatment day 3, 7 and 14 clinical symptom score | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in VAS between two groups at day 3, 7 and 14 post treatment day 3, 7 and 14 VAS (aural fullness, otalgia, itching, hearing) | — |
Countries
Thailand
Contacts
Public ContactNathnicha Kittipibul
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed