Hypertrophic or keloidal mastectomy scars 595-nm pulsed dye laser, female-to-male transgender, hypertrophic scars, keloids, post-mastectomy, transmen
Conditions
Interventions
We performed 595-nm pulsed-dye laser (VBeam Prima, Candela, CA) using the following parameters: spot size 7 mm, fluence 5-7 J/cm2, pulse widths 0.45 ms, 1 pass with 10% overlap with intralesional ster
595-nm pulsed-dye laser with intralesional steroids injection,Intralesional steroids injection
Sponsors
Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Transmen with age at least 18 years old who received testosterone hormonal therapy with symmetrical characteristic of hypertrophic scars (HTS) or keloids from mastectomy surgery
Exclusion criteria
Exclusion criteria: History of previous topical, injections or laser treatment within 3 months, cutaneous infection or uncontrolled acne vulgaris at the target area, immunocompromise status, history of skin cancer, pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical improvement 0, 1, 2, 3, 4, 6, 9 months Vancouver scar scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Scar melanin level 0, 1, 2, 3, 4, 6, 9 months Antera 3D,Scar texture 0, 1, 2, 3, 4, 6, 9 months Antera 3D,Scar hemoglobin level 0, 1, 2, 3, 4, 6, 9 months Antera 3D,Participant satisfaction 9 months 10-cm VAS,Histopathological change 0 and 9 months H&E, Alcian blue, VVG | — |
Countries
Thailand
Contacts
Public ContactSuthinee Rutnin
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Outcome results
None listed