Bacterial Load in the Canal

Investigation of the Effect of Root Canal Shaping with Continuous Irrigation Technique on Bacterial Load in the Canal: A Randomized Controlled Clinical Study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230303001

Enrollment

Registered

2023-03-03

Start date

2022-01-30

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with necrotic single-rooted and single-canal teeth confirmed clinically and by pulpal sensitivity tests Bacterial Load, Continuous Irrigation, Real Time PCR

Interventions

we irrigated the root canal with continious irrigation to reduce bacterial load.,we irrigated the root canal with traditional syringe irrigation to reduce bacterial load.

Experimental Procedure/Surgery,Active Comparator Procedure/Surgery

continious irrigation,traditional syringe irrigation

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Necrotic single-rooted and single-canal teeth confirmed clinically and by pulpal sensitivity tests, 2. PAI index less than 3, 3. Teeth with pocket depth not exceeding 3mm, 4. Teeth that do not show any curvature in the radiography and whose root canal can be followed, 5. Permanent teeth with complete root development, 6. Teeth that can easily reach the apex with 15 K file, 7. Patients between the ages of 18-65, 8. Teeth that have not undergone endodontic treatment before

Exclusion criteria

Exclusion criteria: 1. Patients who did not agree to participate in the study 2.Patients with any systemic disease, 3. Patients who have received antibiotic treatment in the last week, 4. Patients who are pregnant or suspected of pregnancy 5.Teeth with excessive crown destruction that does not allow rubber-dam placement, 6. Teeth with root fracture or pathological mobility, 7. Presence of any resorption in the related tooth, 8.Patients with swelling and palpation, 9. Patients who can not be completed in a single appointment 10. Patients whose sterility sample (after access cavity preparation) did not give negative results for bacteria, 11.Patients whose infected sample (before root canal preparation) did not show a positive result for bacteria

Design outcomes

Primary

Measure	Time frame
bacterial load at same appointment Real time PCR	—

Secondary

Measure	Time frame
N/A N/A N/A	—

Countries

Turkey

Contacts

Public Contactaziz sahin erdogan

ataturk university

sahin.erdogan@atauni.edu.tr0094422360944

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026