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A deep learning model for glaucoma diagnosis based on optical coherence tomography (OCT) : a multicenter study

A deep learning model for glaucoma diagnosis based on optical coherence tomography (OCT) : a multicenter study

Status
Unknown
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20230227003
Enrollment
500
Registered
2023-02-27
Start date
2023-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

OCT data of glaucoma patients and normal population for developing deep learning model glaucoma deep learning model optical coherence tomography

Interventions

Patients who diagnosed glaucoma by vertical cup to disc ratio more than 0.5 with increased IOP more than 21 mmHg or glaucomatous visual field defect ,Normal subject without glaucoma after complete oph
Diagnostic,Diagnostic
Patients who diagnosed glaucoma ,Normal subject without glaucoma

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with age over 18 years old 2. Patients who diagnosed glaucoma 400 eyes 3. Normal subject without glaucoma 100 eyes 4. Each subject should have OCT result and HVF 24-2 result within the same period (not more than 6 months apart)

Exclusion criteria

Exclusion criteria: 1. Patients with ocular comorbidities which obscure OCT data gathering 2. OCT signal strength less than 6 3. Patient with other comorbidities which interfere HVF 24-2 result e.g. retinal disease or neuro-ophthalmologic disease 4. Unreliable HVF result (fixation loss > 20%, false positive > 20%, false negative > 20%, rim artifact, lid effect, clover leaf)

Design outcomes

Primary

MeasureTime frame
efficacy of the model end of study AUC, true positive, true negative, sensitivity, specificity

Secondary

MeasureTime frame
correlation between predicted outcome from the model based on OCT versus HVF 24-2 result end of study comparison of visual field index (VFI) using independent sample T-Test

Countries

Thailand

Contacts

Public ContactDarin Sakiyalak

Faculty of Medicine Siriraj Hospital, Mahidol University

rr.sioph@gmail.com024198037

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026