Cortical excitability study in person with sleep bruxism during pre- and post- treatment with botulinum toxin A injection

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20230224002

Enrollment

Registered

2023-02-24

Start date

2023-12-08

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sleep bruxism Bruxism, Cortical excitability, Cortical silent period, Masseter inhibitory reflexes, Masseter

Interventions

subject identified as having bruxism in accordance with the international consensus definition of bruxism

Basic Science

Sleep bruxism patient

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: subject identified as having bruxism in accordance with the international consensus definition of bruxism

Exclusion criteria

Exclusion criteria: 1. previous history of seizure 2. has cardiac pace maker 3. has metal implantation 4. pregnancy - treatment with botulinum toxin A in past three months

Design outcomes

Primary

Measure	Time frame
Cortical excitability Pre-dose and at 4 weeks post-dose Cortical silent period	—

Secondary

Measure	Time frame
Masseter inhibitory reflexes Pre-dose and at 4 weeks post-dose millisecond	—

Countries

Thailand

Contacts

Public ContactJakkrit Amornvit

King Chulalongkorn Memorial hospital

jakkrit.a@chula.ac.th6622564000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026