Effect of five edible plant extracts on telomere length in Thai adults

Study on the efficacy of a synergetic supplement of five edible plant extracts on telomere length in adults

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230222009

Enrollment

Registered

2023-02-22

Start date

2021-11-28

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thai male and female age 50-65 y have stable health status by using fix dose of blood pressure medications or lipid- lowering medication without serious symptoms. telomere length five edible plant extracts Mylife antioxidant Centella asiatica leaves black sesame seed Isolated soy protein guava fruits mangosteen aril

Interventions

Placebo is corn starch 500 mg/ capsule. Precipitants took 5 capsules/day (2 capsules 30 min before breakfast and 3 capsules 30 min before dinner) for 8 weeks (at week 8 to week 16 of the study periods

Placebo Comparator Other,Active Comparator Dietary Supplement

placebo,five edible plant extracts

Eligibility

Sex/Gender

All

Age

50 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Body mass index 20-24.9 kg/m2 2.Had stable health status by using fix dose of blood pressure medications or lipid- lowering medication without serious symptoms

Exclusion criteria

Exclusion criteria: 1. Female went through menopause for less than 6 months. 2. Type 2 DM 3. Renal diseases 4. Hepatic diseases 5. Thyroid disorder 6. Cancer 7. Anemia 8. Pregnant women 9. Lactating women 10. Take any supplements in the pass 1 month 11. Injected vaccine in the pass 1 month 12. Infected with COVID 19 in the pass 1 month

Design outcomes

Primary

Measure	Time frame
Leukocyte telomere length at week 0, 4, 8, 12, 16 of study period Real time polymerase chain reaction with standard DNA	—

Secondary

Measure	Time frame
plasma total antioxidant capacity at week 0, 4, 8, 12, 16 of study period FRAP assay,CD3 positive T cells at week 0, 4, 8, 12, 16 Flowcytometer,CD4 positive T cells at week 0, 4, 8, 12, 16 Flowcytometer,CD8 positive T cells at week 0, 4, 8, 12, 16 Flowcytometer,serum lipid profile at week 0, 4, 8, 12, 16 colorimetric ,blood glucose at week 0, 4, 8, 12, 16 enzymatic colorimetric,hemoglobin at week 0, 4, 8, 12, 16 colorimetric,BUN and creatinine at week 0, 4, 8, 12, 16 colorimetric,uric acid at week 0, 4, 8, 12, 16 colorimetric,SGOT and SGPT at week 0, 4, 8, 12, 16 colorimetric,HbA1C at week 0, 4, 8, 12, 16 colorimetric,Body composition at week 0, 4, 8, 12, 16 Body composition analyser	—

Measure

Time frame

plasma total antioxidant capacity at week 0, 4, 8, 12, 16 of study period FRAP assay,CD3 positive T cells at week 0, 4, 8, 12, 16 Flowcytometer,CD4 positive T cells at week 0, 4, 8, 12, 16 Flowcytometer,CD8 positive T cells at week 0, 4, 8, 12, 16 Flowcytometer,serum lipid profile at week 0, 4, 8, 12, 16 colorimetric ,blood glucose at week 0, 4, 8, 12, 16 enzymatic colorimetric,hemoglobin at week 0, 4, 8, 12, 16 colorimetric,BUN and creatinine at week 0, 4, 8, 12, 16 colorimetric,uric acid at week 0, 4, 8, 12, 16 colorimetric,SGOT and SGPT at week 0, 4, 8, 12, 16 colorimetric,HbA1C at week 0, 4, 8, 12, 16 colorimetric,Body composition at week 0, 4, 8, 12, 16 Body composition analyser

—

Countries

Thailand

Contacts

Public ContactSiriporn Tuntipopipat

Institute of Nutrition Mahidol University

siriporn.tun@mahidol.ac.th6628002380

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026