Comparative Outcomes of Dextrose Prolotherapy Versus Intra-articular Corticosteroid Injection in Patients with Osteoarthritis Knee, Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230222002

Enrollment

Registered

2023-02-22

Start date

2021-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis knee Prolotherapy, steroid, intraarticular injection, osteoarthritis knee, VAS, WOMAC

Interventions

Dextrose prolotherapy injection in 22 patients,Triamcinolone injection in 22 patient

Active Comparator Drug,Active Comparator Drug

Prolotherapy,Steroid

Eligibility

Sex/Gender

All

Age

45 Years to 75 Years

Inclusion criteria

Inclusion criteria: patients age 45-75 years old, OA knee grade II-III, knee pain at least 3 months, visual analog scale (VAS) more or equal than 3

Exclusion criteria

Exclusion criteria: dextrose, xylocaine or steroid allergy, history of knee replacement surgery, pregnancy, on anti-coagulant therapy, intraarticular injection therapy in last 3 months, secondary osteoarthritis knee such as gouty arthritis, psoriatic arthritis or septic arthritis, external wound or abscess around the knee, unwilling to stop taking NSAIDs after treatment and platelet count < 100,000 cell/mm3

Design outcomes

Primary

Measure	Time frame
Visual analog scale 24 week ask for pain score	—

Secondary

Measure	Time frame
Western Ontario and McMaster osteoarthritis index 24 wk ask for quality of life	—

Countries

Thailand

Contacts

Public ContactTin Chaisongkram

Rajavithi hospital

max.topspin@gmail.com0874172638

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026