All patients over the age of 18 who have been scheduled for bronchoscope to get the tissue diagnosis from the peripheral lung lesions at the pulmonary unit, Chulalongkorn Hospital Rapid on-site cytology evaluation (ROSE), Radial Probe endobronchial ultrasound (RP-EBUS), Transbronchial lung biopsy, Peripheral pulmonary lung lesion, Bronchial brushing, Bronchus sign
Conditions
Interventions
Once the target site was located, bronchial brushing was done, then cytologist evaluate a cytology by using ROSE.the next step is transbronchial biopsy immediately.Once it has been done 3 times, wheth
Experimental Procedure/Surgery,No Intervention Procedure/Surgery
RPEBUS with bronchial brushing with ROSE,RPEBUS with bronchial brushing
Sponsors
King Chulalongkorn Memorial hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. All patients over 18 years old 2.All patients diagnosed with peripheral lung lesions or nodule size smaller than or equal to 3 centimeters from chest computed tomography.
Exclusion criteria
Exclusion criteria: Patients who have bronchoscopy contraindications -No consent for the procedure -Patients do not cooperate during the procedure. -Risk of hemorrhagic conditions such as Severe Thrombocytopenia (Platelet <20000) , Coagulopathy ( INR < 2) that have not been resolved. -Severe or refractory hypoxia (SpO2 < 90%) -Unstable Hemodynamic Status : BP <90/60, MAP < 65, HR < 50 or > 130, RR>30 -Myocardial Infarction within 4-6 weeks -Patients who increased intracranial pressure -Severe pulmonary arterial hypertension -Other relative contraindication conditions depend on judgement of doctor, such as uremia and Superior Vena Cava Obstruction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diagnosis yield of peripheral lung lesions or nodules from the use of rapid on-site cytological evaluation (ROSE) during REBUS transbronchial biopsy and brushing in versus the control group. immediately after procedure diagnostic yield of peripheral lung lesion | — |
Secondary
| Measure | Time frame |
|---|---|
| duration of RP-EBUS, sedative doses, amounts of blood loss of RP-EBUS transbronchial biopsy and brushing in peripheral lung lesions between ROSE group versus control groups. immediate after procedure duration of procedure time, sedative dose, amount blood loss | — |
Countries
Thailand
Contacts
Public Contactkulchamai kulchamai
Faculty of medicine, Chulalongkorn university
Outcome results
None listed