Osteoarthritis of the knee Osteo Arthritis Knee
Conditions
Interventions
Peripheral blood centrifuge at 300 G for 5 min, separate the plasma and buffy coat layers, and then centrifuge at 700 G for 17 min with calcium chloride at the ratio of 1:5 to PRP by volume.
,Centrifu
Leukocyte-rich platelet-rich plasma,Leukocyte-poor platelet-rich plasma,Corticosteroid
Sponsors
Queen Savang Vadhana Memorial Hospital
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Age greater than or equal to 50 years old, Plain radiographs knee AP shows Kellgren-Lawrence classification 1-4, Refuse the use of NSAIDs for 2 weeks.
Exclusion criteria
Exclusion criteria: 1) Previous intra-articular injection therapy in the past 6 months; 2) Previously treated with intra-knee PRP injection; 3) History of knee arthritis from other causes such as rheumatoid arthritis, pseudogout or infectious joints 4) History of blood disorder including anemia and thrombocytopenia (Hb < 12 g/dl, plt < 150,000/ml ) 5) History of surgery on the aforementioned knee 6) Obvious knee deformity (valgus > 15, varus > 20, flexion ROM < 90, extension lag > 20) 7) Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC 6 months The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionare | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS pain 6 months Visual analogue scale for pain,the time up and go test 6 months stands up upon therapist command walks 3 meters, turns around, walks back to the chair and sits down,30-second chair stand test unit second 6 months rise to a full standing position, then sit back down again. repeat for 30 seconds | — |
Countries
Thailand
Contacts
Public ContactKongphop Ratanachai
Queen Savang Vadhana Memorial Hospital
Outcome results
None listed