Healthy Polynucleotide, Periorbital Rejuvenation
Conditions
Interventions
Patients were treated with polynucleotide at periorbital for 3 sessions every 4 weeks. Then they were instructed to follow up at 1 month, 3 months, 6 months after the last treatments.
Experimental Device
Sponsors
SW HEALTHCARE CO.,LTD
Eligibility
Sex/Gender
All
Age
25 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Aged 25-55 years old 2. Both male and female 3. Grade 1-5 wrinkle at periorbital by Wrinkle Assessment Scale of periorbital lines
Exclusion criteria
Exclusion criteria: 1. Subjects who are pregnant 2. Subjects who had history of low platelet, coagulopathy or taking medicine of antocoagulant drug like warfarin 3. Subjects who has dermatits, wound or infection at treatment area 4. Subjects who allergy to anesthesia cream 5. Subjects who taken oral or injection contraceptive pills 6. Subjects who had history of laser, filler and botox at treatment area within 6 months before arrived the project 7. Subjects who had history of keloid or hypertrophic scar 8. Subjects who had history of psychitic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average Wrinkle and Texture Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Antera | — |
Secondary
| Measure | Time frame |
|---|---|
| Volume change Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Vectra,Melanin index Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. mexameter,Erythema Index Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Mexameter,Skin elasticity Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Cutometer,Skin hydration Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Corneometer,Skin lightness Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Colorimeter,Sebum index Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. sebumeter,Physician improvement scale Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Percent improvement,Patient improvement scale Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. percent improvement,safety Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments adverse effect | — |
Countries
Thailand
Contacts
Public ContactRungsima Wanitphakdeedecha
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed