Healthy Platelet-rich plasma, neck rejuvenation, hyaluronic acid
Conditions
Interventions
Patients were treated with Platelet-rich plasma combined with hyaluronic acid at neck for 3 sessions every 4 weeks. Then they were instructed to follow up at 2 weeks, 1 month, 2 months, 3 months, 6 m
Experimental Device
Sponsors
ASTRACO MEDICAL NETWORKS LTD.
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 30-60 years old 2. Both male and female 3. Neck laxity grade 1-5 from Wrinkle Assessment Scale of horizontal neck folds
Exclusion criteria
Exclusion criteria: 1. Subjects who are pregnant 2. Subjects who had history of low platelet, coagulopathy or taking medicine of antocoagulant drug like warfarin 3. Subjects who has dermatits, wound or infection at treatment area 4. Subjects who allergy to anesthesia cream 5. Subjects who taken oral or injection contraceptive pills 6. Subjects who had history of laser at treatment area within 6 months before arrived the project 7. Subjects who had history of keloid or hypertrophic scar 8. Subjects who had history of psychitic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average Wrinkle and Texture Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments Antera | — |
Secondary
| Measure | Time frame |
|---|---|
| Volume change Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments Vectra,Melanin index Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments mexameter,Erythema Index Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments Mexameter,Skin elasticity Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments Cutometer,Skin hydration Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments Corneometer,Skin lightness Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments Colorimeter,Sebum index Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments sebumeter,Physician improvement scale Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments Percent improvement,Patient improvement scale Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments percent improvement,safety Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments adverse effect | — |
Countries
Thailand
Contacts
Public ContactRungsima Wanitphakdeedecha
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed