COVID-19 patients with olfactory dysfunction COVID-19, Delta strain, loss of smell, olfactory dysfunction, hyposmia, early recovery, prognostic factor
Conditions
Interventions
COVID-19 patients who confirm with RT-PCR with new onset of smell dysfunction which confirm with the smell test kit
Other
COVID-19 patients with olfactory dysfunction
Sponsors
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age > 18years 2. Confirmed COVID-19 test identified through nasal swabs and positive reverse transcriptase polymerase chain reaction (RT-PCR) with new onset of smell dysfunction
Exclusion criteria
Exclusion criteria: 1. History of smell loss before COVID-19 era. 2. Previous history of rhinological diseases such as chronic rhinosinustis, nasal tumor, anatomical abnormalities of the nose. 3. Previous neurosurgical, otorhinolaryngological or maxillofacial surgery that cause alteration in sinonasal apparatus. 4. Pregnancy 5. Dementia, or other conditions associated with an inability to complete the evaluations. 6. The patients who refuse to enroll the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prevalence of early olfactory recovery 2 weeks after first evaluation the complete improvement of ten in the VAS score of smell sensation on each specific odor in the first two weeks of follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. factors associated with early olfactory recovery 2. median time to complete recovery of smell loss 6 weeks after first evaluation 1. Odd ratio was used to find associated factors and early olfactory recovery 2.median time is the time participants reached the total smell score of four specific odors | — |
Countries
Thailand
Contacts
Public ContactPattraporn Kreesaeng
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Outcome results
None listed