change of pain-VAS score in acute gout flare between 2 arms Acute gout flare, topical NSAIDs, NSAIDs spray, gout
Conditions
Interventions
Colchicine 1.2 mg stat then 0.6 po q 12 hr plus 1%diclofenac sodium spray total 7 day,Colchicine 1.2 mg stat then 0.6 po q 12 hr plus NSS spray total 7 day
Active Comparator Drug,Placebo Comparator Drug
1%diclofenac sodium spray ,NSS spray
Sponsors
Navamindradhiraj University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Patient age 18 year or more 2.Patient classified having gout with ACR/EULAR classification criteria 2015 present with Acute arthritis
Exclusion criteria
Exclusion criteria: Participant can not communicate or follow command : confusion, coma Contraindications for colchicine, topical NSAIDs Concomitant with other diagnosis : RA, PSA, septic arthritis, CPPD ICU patient : post cardiac arrest, septic shock, acute respiratory failure on ventilator NSAIDs, steroid, colchicine before start treatment Initial eGFR below 30 ml/min/1.73m2 Acute gout flare duration > 5 day
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain 2 day after treatment Visual analogue scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety 7 day Patient report, Creatinine, AST, ALT, ALT,Safety 2 day Patient report | — |
Countries
Thailand
Contacts
Public ContactAksika Saling
Faculty of Medicine Vajira Hospital Navamindradhiraj University
Outcome results
None listed