Older adults with xerostomia for at least a week. Xerostomia, Artificial saliva, Beta-glucan, antioxidant, Moisturizing effect, Total Antioxidant Capacity.
Conditions
Interventions
Artificial saliva solution developed by Chiangmai university (with beta-glucan 1.5% weight by volume).
The spray must be used daily for 4 weeks.
,Artificial saliva solution developed by Chiangmai
Artificial Saliva plus Beta-glucan ,Artificial Saliva developed by Chiangmai university
Sponsors
Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Subjects age older than 60 years old 2.Subjects that have experienced subjective feelings of dry mouth for more than 7 days
Exclusion criteria
Exclusion criteria: 1) Subjects have previous radiation therapy (head and neck area) 2) Subjects have previous chemotherapy 3) Subjects have cancer or tumor of the salivary gland. 4) Subjects have a history of systemic diseases explaining the diminished salivary flow (i.e., Sjogren syndrome, infection of the salivary glands,) 5) Pregnant or breastfeeding women 6) Decompensated systemic disorders or cognitive problems. 7) Subjects have immunodeficiency diseases 8) Subjects who are allergic to fungal or yeast
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Xerostomia Inventory (XI) 4 weeks Xerostomia Inventory (XI) score | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical oral dryness score (CODS) 4 weeks Clinical oral dryness score (CODS) (0-10),Oral moisture degree in patients with dry mouth measure by oral moisture checking device 4 weeks scale(0-99.9),The whole unstimulated saliva flow rate 4 weeks ml/min,Salivary total antioxidant capacity 4 weeks Salivary TAC,Evaluation of post-use satisfaction with artificial saliva spray 4 weeks Satisfaction score(1-5) | — |
Countries
Thailand
Contacts
Public ContactKathawut Tachasuttirut
Chiang Mai University
Outcome results
None listed