healthy human volunteers Working memory, acetylcholinesterase, monoamine oxidase
Conditions
Interventions
Sponsors
Rajamangala university of technology Isan
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Subjects: Aged 45-70 years, 2. Healthy status, 3. Located in the northeastern region of Thailand., 4. Two days before the testing, it is prohibited to consume tea, coffee, or alcohol for at least 12 hours., 5. Montreal Cognitive Assessment (MoCA) Test more than 26
Exclusion criteria
Exclusion criteria: 1. Cardiovascular diseases, respiratory diseases, neuropsychological diseases, head injury, diabetes mellitus, liver disease, cancer, autoimmune disease, and hematological disorder, 2. Receiving drugs or hormones, dietary supplements, or other types of herbal medicines that affect the nervous system during the trial and within three months prior to the start of the trial, 3. Alcohol abuse, 4. Smoking status (more than 10 cigarettes per day), 5. In the process of collaborating with different projects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| working memory at week-4 and week-8 Computerized Battery Test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Acetylcholinesterase (AChE) Activity and Monoamine Oxidase Activity Baseline and week 8 Biochemical Assays,Clinical safety assessment Baseline and week-8 biochemistry and hematology | — |
Countries
Thailand
Contacts
Public ContactWarin Ohnon
Faculty of Natural Resources
Outcome results
None listed