A randomized trial of surgically induced total corneal astigmatism and outcomes in small versus conventional cataract incisions

Total corneal power changes and surgical outcomes of small vs. traditional corneal incision size for phacoemulsification: RCT

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230202010

Enrollment

200

Registered

2023-02-02

Start date

2023-03-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total cornel power changes and surgical outcomes of small vs traditional corneal incision size for phacoemulsification Small incision Phacoemulsification Cataract Surgical induced astigmatism Total keratometry

Interventions

Small corneal incision size for phacoemulsification is 2.4 mm.,Traditional corneal incision size for phacoemulsification is 3.00 mm.

Experimental Procedure/Surgery,Active Comparator Procedure/Surgery

Small corneal incision size for phacoemulsification,Traditional corneal incision size for phacoemulsification (3mm)

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed with senile cataract and considered cataract surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with history of other ocular diseases that effects visual acuity 2. history of corneal ulcer 3. history of eye injury 4. history of major ocular surgery 5. dry eye disease (Oxford score > grade 2) 6. history of using oral/topical drugs causing dry eye symptoms 7. Patients who want to use the IOL other than the one used in this research 8. Patients who cannot cooperate during the eye examination and surgery

Design outcomes

Primary

Measure	Time frame
Post cataract surgery surgically induced astigmatism calculated from total keratometry 3 months Total keratometry derived from swept-source OCT-based biometer	—

Secondary

Measure	Time frame
Difference of surgically induced astigmatism calculated from conventional keratometry and total keratometry 1 month Conventional and Total keratometry derived from swept-source OCT-based biometer,Difference of surgically induced astigmatism calculated from conventional keratometry and total keratometry 3 months Conventional and Total keratometry derived from swept-source OCT-based biometer,Post operative visual acuity 1 day ETDRS LogMAR visual acuity score,Post operative visual acuity 1 week ETDRS LogMAR visual acuity score,Post operative visual acuity 1 month ETDRS LogMAR visual acuity score,Post operative visual acuity 3 months ETDRS LogMAR visual acuity score,Post operative predictive error 1 month refractive error measured in diopter (D) unit,Post operative predictive error 3 months refractive error measured in diopter (D),Post operative complication 3 months event count,Post operative dry eye symptoms 3 months SPEED dry eye questionnaire score	—

Measure

Time frame

Difference of surgically induced astigmatism calculated from conventional keratometry and total keratometry 1 month Conventional and Total keratometry derived from swept-source OCT-based biometer,Difference of surgically induced astigmatism calculated from conventional keratometry and total keratometry 3 months Conventional and Total keratometry derived from swept-source OCT-based biometer,Post operative visual acuity 1 day ETDRS LogMAR visual acuity score,Post operative visual acuity 1 week ETDRS LogMAR visual acuity score,Post operative visual acuity 1 month ETDRS LogMAR visual acuity score,Post operative visual acuity 3 months ETDRS LogMAR visual acuity score,Post operative predictive error 1 month refractive error measured in diopter (D) unit,Post operative predictive error 3 months refractive error measured in diopter (D),Post operative complication 3 months event count,Post operative dry eye symptoms 3 months SPEED dry eye questionnaire score

—

Countries

Thailand

Contacts

Public ContactChareenun Chirapapaisan

Faculty of Medicine Siriraj Hospital, Mahidol University

chareenun@gmail.com0877109959

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026