Patient with melasma Leukocyte poor Platelet-rich plasma, melasma
Conditions
Interventions
Patients were treated with Leukocyte poor Platelet-rich plasma 3 sessions every 4 weeks. Then they were instructed to follow up at 2 weeks, 1 month, 2 months, 3 months, 6 months after the last treatme
Experimental Device
Leukocyte poor Platelet-rich plasma
Sponsors
ASTRACO MEDICAL NETWORKS LTD.
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years 2. Asian 3. were diagnosed with melasma by dermatologist
Exclusion criteria
Exclusion criteria: 1. Subjects who are pregnant 2. Subjects who had history of low platelet, coagulopathy or taking medicine of antocoagulant drug like warfarin 3. Subjects who has dermatits, wound or infection at treatment area 4. Subjects who allergy to anesthesia cream 5. Subjects who taken oral or injection contraceptive pills 6. Subjects who had history of melasma treatment within 6 months before arrived the project 7. Subjects who had history of laser at treatment area within 6 months before arrived the project 8. Subjects who had history of keloid or hypertrophic scar 9. Subjects who had history of psychitic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average melanin concentration Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments Antera | — |
Secondary
| Measure | Time frame |
|---|---|
| Melanin index Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments mexameter,Erythema Index Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments mexameter,safety Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments adverse effect,Physician improvement scale Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments Percent improvement,Patient improvement scale Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments percent improvement,MASI Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments MASI score | — |
Countries
Thailand
Contacts
Public ContactRungsima Wanitphakdeedecha
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed