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Innovative Determination of Optimal Positive Expiratory Pressure to Increase Exercise Tolerance in COPD patients

Innovative Determination of Optimal Positive Expiratory Pressure to Increase Exercise Tolerance in COPD patients

Status
Unknown
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230124006
Enrollment
47
Registered
2023-01-24
Start date
2023-01-31
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease COPD Exercise Dyspnea Dynamic hyperinflation

Interventions

Participants perform spot marching tests with the calculated levels of Positive expiratory pressure.,Participants perform spot marching tests without Positive expiratory pressure.
Experimental Other,Sham Comparator Other
Positive expiratory pressure,Sham

Sponsors

Khon Kaen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. COPD patients GOLD stage II to IV. 2. Age between 40 to 80 years old. 3. Good communication, cooperation, and cognition. 4. Stable COPD (without acute exacerbation in the previous 4 weeks).

Exclusion criteria

Exclusion criteria: 1. Medical diagnosis history of cardiovascular disease or related to the contraindication of exercise. 2. Home oxygen therapy (for at least 15 hours per day) or SpO2 < 88%. 4. Neuromuscular and musculoskeletal disorders. 5. Recent surgery. 6. Spontaneous bone fracture. 7. Acute lung embolism, lung infraction, or infection. 8. Severe arterial hypertension (Resting of systolic >200 mmHg or diastolic of >110 mmHg).

Design outcomes

Primary

MeasureTime frame
Exercise time End exercise time

Secondary

MeasureTime frame
Dynamic hyperinflation End exercise Inspiratory capacity,Rate perceive of breathlessness Isotime Borg Dyspnea score

Countries

Thailand

Contacts

Public ContactNimit Kosura

Faculty of Associated Medical Science, Khon Kaen University

Nimit_k@kkumail.com0963235566

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026