Laser-induced post-inflammatory hyperpigmentation Solar lentigines, Q-switched Nd: YaG lasers, Laser-induced post-inflammatory hyperpigmentation, Isobutylamido thiazolyl resorcinol
Conditions
Interventions
Apply topical ITR at solar lentigine for twice daily 2 weeks prior to perform Q-switch Nd: Yag 532-nm at the lesion,Apply topical ITR at solar lentigine for once daily 2 weeks prior to perform Q-switc
Apply ITR at solar lentigines twice daily,Apply ITR at solar lentigines once daily,No application
Sponsors
Dermatology department, Faculty of Medicine, Ramathibodi hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 18 years or older who had solar lentigines on their arms.
Exclusion criteria
Exclusion criteria: History of laser therapy at the lesions within 3 months prior to the study, active infection or inflammation at the treatment site, immunocompromised status, history of skin cancers or keloids, history of immunosuppressive drugs or vitamin A derivatives used, pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melanin index Baseline, 2, 4, 6 and 8 weeks post-laser Antera 3D,Luminance score Baseline, 2, 4, 6 and 8 weeks post-laser Colormeter,Incidence of post-inflammatory hyperpigmentation 4, 6 and 8 weeks post-laser Clinically diagnosis by a blinded dermatologist | — |
Secondary
| Measure | Time frame |
|---|---|
| Hyperpigmentation severity score 4, 6 and 8 weeks post-laser A blinded dermatologist using 10-cm visual analogue sc,Hyperpigmentation severity score 4, 6 and 8 weeks post-laser Participants using 10-cm visual analogue scale | — |
Countries
Thailand
Contacts
Public ContactVasanop Vachiramon
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Outcome results
None listed