Potential Combination of Thai Natural Extracts for an Anti-Aging Facial Moisturizer: Skin irritation test, efficacy evaluation and satisfaction of volunteers

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230117007

Enrollment

Registered

2023-01-17

Start date

2020-09-07

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ageing skin ageing skin

Interventions

Anti-aging moisturizer in a form of cream containing water, glycerin, butylene glycol, sorbitol, caprylhydroxamic acid, 1,2-hexanediol, disodium EDTA, glyceryl stearate, ceteareth-20, PEG-75 stearate,

Experimental Other,Placebo Comparator Other

Anti-aging moisturizer,Placebo moisturizer

Eligibility

Sex/Gender

Female

Age

40 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. be able to inform consent 2. be able to follow the instruction of the research strictly 3. be 40 - 60 years old 4. be a woman 5. be healthy without any congenital skin disease 6. not have any current skin disease such as atopic dermatitis 7. be not allergic to substances 8. be not in a special treatment for any disease 9. not have any tattoo or wound or skin disorder at the tested skin area

Exclusion criteria

Exclusion criteria: 1. be not able to inform consent 2. be not able to follow the instruction of the research strictly 3. have a congenital skin disease 4. have current skin diseases such as atopic dermatitis 5. be allergic to substances 6. be in a special treatment for any disease 7. have tattoos or wounds or skin disorders at the tested skin area 8. be a volunteer in other clinical research

Design outcomes

Primary

Measure	Time frame
skin hydration at the beginning of study, Day 30, Day 60 corneometer unit,skin elasticity at the beginning of study, Day 30, Day 60 skin elasticity recovery,skin wrinkle at the beginning of study, Day 30, Day 60 surface,skin wrinkle at the beginning of study, Day 30, Day 60 volume,skin wrinkle at the beginning of study, Day 30, Day 60 the height of the skin furrow,skin wrinkle at the beginning of study, Day 30, Day 60 the arithmetic average of the skin roughness	—

Measure

Time frame

skin hydration at the beginning of study, Day 30, Day 60 corneometer unit,skin elasticity at the beginning of study, Day 30, Day 60 skin elasticity recovery,skin wrinkle at the beginning of study, Day 30, Day 60 surface,skin wrinkle at the beginning of study, Day 30, Day 60 volume,skin wrinkle at the beginning of study, Day 30, Day 60 the height of the skin furrow,skin wrinkle at the beginning of study, Day 30, Day 60 the arithmetic average of the skin roughness

—

Secondary

Measure	Time frame
satisfaction Day 60 satisfactory score	—

Countries

Thailand

Contacts

Public ContactWorrapan Poomanee

Faculty of Pharmacy, Chiang Mai University

worrapan.p@cmu.ac.th0819524708

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026