Chemotherapy induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy, which has a serious impact on the quality of life of patients. At present, there is no targeted and reliable treatment plan. To investigate the efficacy and safety of acupuncture combined with moxibustion in the treatment of CIPN, a randomized controlled trial was conducted. Acupuncture
Conditions
Interventions
Acupuncture point selection: Hegu (LI4), Taichong (LR3), Quchi (PC3), Neiguan (PC6), Zusanli (ST36), Xuehai (SP10), Fenglong (ST40), Yanglingquan (GB34), Shixuan (EX-UE11), Sanyinjiao (SP6), Taixi (KI
s Republic of China, Meridian Points Locations [29], and the treatment was completed by professional acupuncturists with more than 5 years of acupuncture and moxibustion experience, and the treatment
Experimental Other
acupuncture combined with moxibustion
Sponsors
Weiyu Chang and Lijiang Ji
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Have received chemotherapy (complete at least one complete cycle), the primary disease condition is stable; (2) Symptoms of chemotherapy-induced peripheral neuropathy after the end of chemotherapy; (3) Age not less than18 years and not more than80 years; (4) Karnofsky's performance status (KPS) score was greater than 60; (5) Predicted survival time not less than 6 months; (6) The patient has signed informed consent.
Exclusion criteria
Exclusion criteria: (1) A history of neuropathy, such as diabetes, multiple sclerosis, HIV and Parkinson's disease; (2) Patients with a variety of drug allergy or allergic constitution; (3) Patients with other neurological diseases, which may affect the evaluation of efficacy; (4) Patients with skin damage or infection at the acupoints that were not suitable for acupuncture or moxibustion; (5) Patients suffering from mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TNS , including 11 scoring items. 4 weeks evaluate the symptoms and signs of peripheral neuropathy, motor and sensory neurophysiology examination, touch, vibration perception, quality of life, etc. | — |
Secondary
| Measure | Time frame |
|---|---|
| evaluate the symptoms and signs of peripheral neuropathy, motor and sensory neurophysiology examination, touch, vibration perception, quality of life, etc. 4 weeks ranging from grade 0 to grade 4 | — |
Countries
China
Contacts
Public ContactLijiang Ji
Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Changshu, Jiangsu province, China
Outcome results
None listed