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Efficacy of local infiltration tramadol (Transversus abdominis plane block technique) versus preemptive intravenous tramadol on postoperative pain after open appendectomy: a prospective randomized controlled trial

Efficacy of local infiltration tramadol (Transversus abdominis plane block technique) versus preemptive intravenous tramadol on postoperative pain after open appendectomy: a prospective randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230111008
Enrollment
32
Registered
2023-01-11
Start date
2021-12-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative pain control in appendicitis patients who undergo open appendectomy Appendectomy Appendicitis Local Tramadol

Interventions

normal saline injection and transversus abdominis plane block technique with tramadol infiltration, the preemptive intravenous tramadol and transversus abdominis plane normal saline infiltration
Active Comparator Drug,Placebo Comparator Drug
Transversus abdominis plane block technique with tramadol infiltration,the preemptive intravenous tramadol injection

Sponsors

Police general hospital,Bangkok
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: preoperative and postoperative diagnosis of acute appendicitis who undergo open appendectomy under general anesthesia

Exclusion criteria

Exclusion criteria: American association of Anesthesiologist (ASA) classification above3, allergy to tramadol or opioid derivatives, unable follow instruction to evaluated pain score, patient with history of chronic pain/ long term opioid used, contraindication to general anesthesia such as malignant hyperthermia or airborne disease and patients who undergo appendectomy with delay suture.

Design outcomes

Primary

MeasureTime frame
Postoperative pain at rest and activity 24hours Visual analogue scale

Secondary

MeasureTime frame
postoperative opioid consumption 24hours Milligram per kilogram,Complications 24hours Side effect (N/V,surgical site infection),Lenght of hospital stay at least 24 hours Hours

Countries

Thailand

Contacts

Public ContactAnakkawee Hsiung

Police general hospital,Bangkok

Anakkawee.hsi@gmail.com0897642192

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026