Randomized double-blind controlled trial: epidural corticosteroid injection for subacute pain control following bilateral total knee arthroplasty

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230111002

Enrollment

Registered

2023-01-11

Start date

2021-05-16

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bilateral knee osteoarthritis patients receiving bilateral TKA surgery knee osteoarthritis total knee replacements

Interventions

Triamcinolone acetonide 40mg(1ml) + 1% lidocaine 5 ml via epidural route,1% lidocaine 6 ml via epidural route

Experimental Drug,Active Comparator Drug

Corticosteroid + Lidocaine,Lidocaine-only

Eligibility

Sex/Gender

All

Age

50 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Bilateral knee osteoarthritis patients receiving bilateral TKA surgery, 2. Age 50-85 years old, 3. ASA class I to III, 4. Patients who are eligible to understand and consent terms of research

Exclusion criteria

Exclusion criteria: 1. Patients who had problems of cognitions and communications, 2. Patients who had chronic kidney disease stage III or more and chronic liver diseases, 3. Patients who allergy to drugs used in this research, 4. Patients who contraindicated for epidural procedures

Design outcomes

Primary

Measure	Time frame
Pain 12 weeks after intervention VAS score	—

Secondary

Measure	Time frame
Functional outcome 12 weeks after intervention modified WOMAC score	—

Countries

Thailand

Contacts

Public ContactSetthawut Suppiumlarp

Police general hospital

setthawut.sup@gmail.com0846559484

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026