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Static Arterial Elastance Ratio to Explain the Physiologic Meaning of Dynamic Arterial Elastance in Sepsis or Septic Shock

The Relationship between Static Arterial Elastance Ratio and Dynamic Arterial Elastance to Explain the Physiologic Meaning of Dynamic Arterial Elastance in Sepsis or Septic Shock

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20230110003
Enrollment
36
Registered
2023-01-10
Start date
2021-09-27
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis or septic shock dynamic arterial elastance, arterial elastance, sepsis, septic shock, arterial impedance, pulse pressure variation, and stroke volume variation.

Interventions

Sepsis or septic shock with dynamic arterial elastance less than 1,Sepsis or septic shock with dynamic arterial elastance more than 1
Basic Science,Basic Science
dynamic arterial elastance less than 1,dynamic arterial elastance more than 1

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) age older than 18 years old; 2) admission from the emergency department or general ward with sepsis or septic shock defined by The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3); 3) on controlled mechanical ventilation, and 4) require fluid challenge by physician's discretion.

Exclusion criteria

Exclusion criteria: cardiac arrhythmia, valvular heart disease, intracardiac shunt, intra-abdominal hypertension, contraindication for sedation, contraindication for using a neuromuscular blocking agent, and pregnancy.

Design outcomes

Primary

MeasureTime frame
Relationship At time of sepsis or septic shock Correlation coeficient

Secondary

MeasureTime frame
Relationship to arterial elastance At time of sepsis or septic shock Correlation coefficient

Countries

Thailand

Contacts

Public ContactPongdhep Theerawit

Faculty of Medicine, Ramathibodi Hospital

pongdhep.the@mahidol.ac.th0818881536

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026