Efficacy of intranasal fentanyl drops as an adjunct for pain management in retinopathy of prematurity screening. Pain, retinopathy of prematurity, intranasal fentanyl
Conditions
Interventions
Intranasal fentanyl (2 mcg/kg) with normal saline solution until 0.3 ml dropped both nostril prior to retinopathy of prematurity screening 5 minutes.,Intranasal normal saline 0.3 ml
Active Comparator Drug,Placebo Comparator Drug
Intranasal fentanyl drop,Intranasal normal saline
Sponsors
Bhumibol Adulyadej Hospital
Eligibility
Sex/Gender
All
Age
4 Weeks to 2 Months
Inclusion criteria
Inclusion criteria: Neonates considered at risk for retinopathy of prematurity received screening included birth weight < 1500 g or gestation age < 30 wks, and retinopathy of prematurity risk even birth weight 1500-2000 g or gestation age > 30 wk with post-menstrual age > 4 wk and underwent retinopathy of prematurity screening
Exclusion criteria
Exclusion criteria: Neonate who needed invasive mechanical ventilation, were hemodynamically unstable, under sedation, with congenital malformation or neurological dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The efficacy of intranasal fentanyl drop as an adjunct for pain management 1 h Premature infant pain profile revised | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety of intranasal fentanyl drop 24 h Observation of adverse event during and after intervention at least 24 h that considered of apnea, respiratory compromise, hemodynamic and feeding intolerance | — |
Countries
Thailand
Contacts
Public ContactNarisa Kanchanathep
Bhumibol Aduyadej hospital
Outcome results
None listed