patients who undergo endoscopic endonasal transsphenoidal surgery intravenous anesthesia propofol inhalation anesthesia desflurane intraoperative visualization endoscopic endonasal transsphenoidal surgery
Conditions
Interventions
Maintenance of anesthesia with propofol target controlled infusion 2-6 mcg/mL and nitrous oxide and fentanyl intravenous infusion 0.2-0.5 mcg/kg/hr. ,Maintenance of anesthesia with 4-8% end-tidal des
Experimental Other,Active Comparator Other
Intravenous anesthesia,Inhalation anesthesia
Sponsors
Faculty of Medicine, Chulalongkorn university
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. patients who undergo endoscopic endonasal transsphenoidal surgery 2. American society of Anesthesiologists physical status I-III
Exclusion criteria
Exclusion criteria: 1. patients who refuse to be included in the project 2. anesthesia without surgery 3. patients who receive combined intravenous and inhalation anesthesia 4. patients with increased intracranial pressure 5. patients with coagulopathy 6. patients with abnormal liver function or chronic alcoholism 7. patients who are malignant hyperthermia susceptibility 8. patients with opioid allergy 9. patients with drug addiction 10. patients who receive preoperative opioids or psychoactive medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraoperative surgical field visualization 1. Middle turbinate displacement 2. Sphenoid sinus enlargement 3. Removal of lesion 4. The end of surgery Boezaart score | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea and vomiting in the postanesthetic care unit every 15 minute in the postanesthetic care unit until 1 hour nausea and vomiting score | — |
Countries
Thailand
Contacts
Public ContactLawan Tuchinda
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed