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The efficacy of ultrasound-guided interpectoral plane block combined with multiple-injection costotransverse block or single-injection erector spinae plane block compared to systemic analgesia for postoperative pain control in breast cancer surgery: A randomized controlled trial

The efficacy of ultrasound-guided interpectoral plane block combined with multiple-injection costotransverse block or single-injection erector spinae plane block compared to systemic analgesia for postoperative pain control in breast cancer surgery: A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230103005
Enrollment
90
Registered
2023-01-03
Start date
2023-01-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain control in breast cancer surgery Breast cancer , breast cancer surgery,costotransverse block ,pain controlled,costotransverse block,erector spinae plane block

Interventions

controlled,- Receive a triple injection of ultrasound-guided MICTB at T3-4, T4-5, and T5-6, using 0.15 ml/kg of 0.25% bupivacaine with 1% lidocaine with epinephrine 1:400000 in each level, total LA of
Placebo Comparator No treatment,Experimental Procedure/Surgery,Experimental Procedure/Surgery
Group control ,Group MICTB ,Group ESPB

Sponsors

Department of Anesthesiology, Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University, Chiang Mai, Thailand
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Female patients aged between 20 and 65 years 2. American Society of Anesthesia (ASA) physical status I - II 3. Scheduled for elective unilateral breast cancer surgery 4. Body weight > 40 kg

Exclusion criteria

Exclusion criteria: 1. Patients with known allergies to any of the study drugs (local anesthetics, opioids, acetaminophen, and codigesic) 2. Underlying chronic kidney disease, liver cirrhosis, major cardiac disease, or pre-existing neurological deficits 3. Recent use of opioid drugs. 4. Morbid obesity (body mass index > 40 kg/m2) 5. Coagulopathy 6. Pre-existing infection at the block site 7. Psychological diseases include bipolar or depression 8. Inability to communicate include deafness or no telephone available 9. Bilateral breast surgery

Design outcomes

Primary

MeasureTime frame
postoperative morphine consumption in the first 24 hours 24 hr post-operative measure by mg,intraoperative fentanyl consumption, postoperative pain scores, block performance data, nausea and vomiting, patient satisfaction. post-op 48hr , 2 wk mg/NRS/pain severity index,patient satisfaction, and the incidence of post mastectomy pain. 2 wk NRS,PSI

Secondary

MeasureTime frame
Total morphine consumption in the first 24 postoperative hours record,present of postmastectomy pain post-op at 2 wk follow up by phone ,first ambulation time (out of bed tome) post operative follow up and record

Countries

Thailand

Contacts

Public ContactArtid Samerchua

Maharaj Nakorn Chiang Mai Hospital

artidsamerchua@gamail.com0826944496

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026