Comparison of desflurane with propofol and desflurane on extubation time in elective craniotomy for supratentorial tumor

Status

Unknown

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20221231002

Enrollment

Registered

2022-12-31

Start date

2023-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the adult patients who had supratentorial tumor. recovery time, anesthesia, propofol, desflurane, time to extubation

Interventions

In Des-Prop group, the patients are anesthetized with the 0.5 MAC of desflurane with titrated propofol dose range of 25-150 mcg/kg/min for maintence BIS in range of 40 - 60. The fentanyl is administra

Experimental Other

Des-Prop group

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. the patients with supratentorial tumor age 18-65 years old. 2. ASA physical status 1-3 3. elective surgery

Exclusion criteria

Exclusion criteria: 1. refused patients 2. Glasgow Coma Score <15 3.history of alcohol or drug abused 4. BMI > 35 kg/m2 5. history of anesthetic drugs allergy 6. pregnant patients

Design outcomes

Primary

Measure	Time frame
time to extubation the end of surgery minutes	—

Secondary

Measure	Time frame
brain relaxation score Intraoperative period score,time to eye opening at the end of surgery minutes,time to follow command at the end of surgery minutes,time to archieve Modified Aldrete Score more than 8 at recovery room minutes,postoperative nausea and vomiting at recovery room yes or no	—

Countries

Thailand

Contacts

Public ContactSunisa Sangtongjaraskul

Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society

sunisa.sa@chula.ac.th026494000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026