Skip to content

Evaluation of the efficacy of bilateral ultrasound-guided single shot Transversus thoracis muscle plane block on hemodynamic stability after median sternotomy in cardiac surgery: A prospective randomized controlled trial

Evaluation of the efficacy of bilateral ultrasound-guided single shot Transversus thoracis muscle plane block on hemodynamic stability after median sternotomy in cardiac surgery: A prospective randomized controlled trial

Status
Unknown
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20221229002
Enrollment
70
Registered
2022-12-29
Start date
2023-01-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Median sternotomy in cardiac surgery is the severe pain operation which lead to both acute and chronic pain in the future. Moreover, stimulating of the sympathetic nervous system is an increment of heart rate and blood pressure associated with aggravate oxygen consumption and an imbalance of the circulatory system which causes to increase on myocardial ischemia. Transversus thoracic muscle plane block is the new regional technique, ability of controlled pain, and sympathetic response. Therefore,

Interventions

Controlled group used 30 ml of normal saline injection bilaterally Transversus thoracic muscle plane block by ultrasound version KONICA SONIMAGE MX1 and frequency 11 to 13 MHz of ultrasound liner pro
Controlled group,Intervention group

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients, who are an elective median sternotomy cardiac surgery cases, admit in The Central Chest Institute of Thailand 2. Age of patients is 18 years or over

Exclusion criteria

Exclusion criteria: 1.BMI of patients is less than 18.5 kilograms per meter square 2. Body weight of patients is less than 40 kilograms 2.LVEF of patients is less than 45 percent 3. Patients use ventilator or IABP or inotropic drugs before operation 4. Patients are Thrombocytopenia or coagulation abnormality 5.Patients need to Reoperation or emergency operation 6. Patients are hemodyalysis chronic renal failure disease 7. Patients are local anesthetic allergy 8. Patients are poor controlled hypertension 9. Patients appear infection at procedural area 10.Patients have communication failure or abnormality of consiousness 11. Patients has aortic surgery

Design outcomes

Primary

MeasureTime frame
Hemodynamic stability 6 months Blood pressure (mmHg), Heart rate (beat per minute)

Secondary

MeasureTime frame
type and dose of intravenous vasodilator drugsvasodila 6 months microgram per kilogram per minute

Countries

Thailand

Contacts

Public ContactAreerat Kaewanuchit

Central Chest Institute of Thailand

kaewanuchit@yahoo.com0614922291

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026