Healthy Thai volunteers (aged 30-60 years old) Skin wrinkle, Moisturizer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Healthy male and female aged 30-60 years of all skin types (normal, dry, oily as well as combination skin) - Having clear visible wrinkle (wrinkle scale level 3 and above) at both eye corners (crows feet) - Having experience of using a counter brand facial skin care - No history of allergy problem to any commercially available anti-wrinkle products - Willing to participate in the project and be able to follow the study protocol - Willing to give a written consent after being informed the study detail - No history of changing facial moisturizing products or dietary supplements within one month before entering the study - Be able to read, communicate and write in Thai language
Exclusion criteria
Exclusion criteria: - History of skin eczema, psoriasis within 6 months before entering the study - Having wound, scar or any skin disease on the evaluation area of the face - History of using steroid, antibiotic, NSAIDs and antihistamine within 3 days before entering the study - History of using topical medicine on the face within 3 weeks before entering the study - Having chronic diseases and continuous taking medicines - History of major operation within 1 year before entering the study - History of skin cancer within 1 year before entering the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin moisturizer 8 weeks Measuring by Corneometer,Skin wrinkle 8 weeks Measuring by Primos | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Cosmetics and natural products research center, Pharmaceutical sciences, NU