Adult patients with type II diabetes mellitus Diabetes Mellitus, Non-Insulin-Dependent
Conditions
Interventions
Centella asiatica capsule,Placebo capsule
Experimental Drug,Placebo Comparator Drug
Sponsors
(in process) the Royal College of Physicians of Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1). Age 18-65 years 2). Willing to participate the study 3). Hemoglobin A1C >6.5% or fasting blood sugar >125 mg/dL
Exclusion criteria
Exclusion criteria: 1).Pregnancy or breastfeeding 2).Type I diabetes mellitus 3).Hypo- or hyperthyroidism 4).Severe hepatic diseases 5).Severe renal disease 6).Allergic to Centella asiatica 7).Currently treated with injected insulin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin A1C 12 weeks percent | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting blood sugar 12 weeks mg/dL,Cytokine (TNF-alpha, IFN-gamma, IL-4, IL-10) 12 weeks pg/mL,Liver function test (AST, ALT) 12 weeks IU/L,Serum creatinine 12 weeks mg/dL,Clinical adverse reactions 12 weeks Clinical adverse reactions,Lipid profile 12 weeks mg/dL | — |
Countries
Thailand
Contacts
Public ContactWeeratian Tawanwongsri
Walailak University
Outcome results
None listed