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Safety and immunogenicity of the third COVID-19 vaccines booster dose in children (12-18 years) with completed 2 doses as recommended by the ministry of public health

Safety and immunogenicity of the third COVID-19 vaccines booster dose in children (12-18 years) with completed 2 doses as recommended by the ministry of public health

Status
Unknown
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20221215006
Enrollment
320
Registered
2022-12-15
Start date
2022-12-19
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health adolescents COVID-19, booster, vaccine

Interventions

This arm is a group of adolescent Thai individuals who received 2 doses of BNT162b2 vaccines. They were enrolled to recieve a booster dose (third dose vaccine) which is Pfizer (PF) full dose after 3
Active Comparator Biological/Vaccine,Active Comparator Biological/Vaccine,Experimental Biological/Vaccine
Booster with PZ in two-dose PZ recipient,Booster with PZ in two-dose SP recipient,Booster with Covovax in two-dose SP or BNT162b2 recipient

Sponsors

Chulalongkorn University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Healthy adolecents (aged between 12-18 years) who have previously received two doses following the ministry of public health (official proof of vaccinations required). 2. Have received your second dose of COVID-19 vaccine more than 3 months. 3. Have or Have not previously had COVID-19 infection. 4. are not in immunocompromised states (chronic diseases or immunodeficiency disorder) 5. No oallergies to the vaccine components 6. Are available for follow-ups and blood draws

Exclusion criteria

Exclusion criteria: 1. Immunodeficiency status 2. Do not agree to participate 3. Severe coagulopathy

Design outcomes

Primary

MeasureTime frame
immunogenicity 1 month neutralizing antibody against BA.5

Secondary

MeasureTime frame
safety 1 month Frequency of adverse events

Countries

Thailand

Contacts

Public ContactNasamon Wanlapakorn

Faculty of Medicine, Chulalongkorn University

nasamon.w@chula.ac.th0817317393

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026