PLATELET AGGREGATION THAI HERBAL WATTANA FORMULA HERBAL MEDICINE PLATELET AGGREGATION INNATE DHATU RUEAN METABOLOMICS
Conditions
Interventions
Received a single dose of WNF 1,000 mg
Experimental Drug
THAI HERBAL WATTANA FORMULA
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
32 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Male or female Thai nationality greater than or equal to 32 years at enrollment 2. Body mass index (BMI) between 18-24 kg/m2 3. Healthy as confirmed by blood chemistry especially AST less than or equal to 40 U/L (in male), less than or equal to 32 U/L (in female); ALT less than or equal to 41 U/L (in male), less than or equal to 33 U/L (in female); ALP less than or equal to 141 U/L (in male), less than or equal to 105 U/L (in female) and GFR greater than or equal to 60 ml/min/1.73m2 4. Willingness to participate in the study and sign the informed consent
Exclusion criteria
Exclusion criteria: 1. Evidence of allergic reactions from herbal medicine 2. History of taking coffee, tea or caffeinated beverages consumption within 14 days before the study 3. History of taking dietary supplements and vitamins within 14 days before the study 4. Habitual smoking and cannot instruct to abstain from cigarettes during the study 5. History of excess alcohol ingestion and cannot instruct to abstain from alcohol during the study or drug abuse 6. Pregnant or breastfeeding 7. History of blood donated or received within 3 months before the study 8. History of participated in the research study within 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PLATELET AGGREGATION at 3, 6, and 24 hours after dosing Aggregation platelet status/ Percent platelet aggregation | — |
Secondary
| Measure | Time frame |
|---|---|
| plasma metabolomics at 3, 6, and 24 hours after dosing plasma metabolic profiles perform by PCA, OPLS-DA,S-Plot | — |
Countries
Thailand
Contacts
Public ContactSuveerawan Limsuvan
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed