Patient who undergoes elective surgery with general anesthesia that have indication for arterial line insertion Norepinephrine, Arterial line insertion, Success rate, Number of attempts
Conditions
Interventions
Norepinephrine 5 mcg IV push 1 min before arterial line insertion,NSS 5 ml IV push 1 min before arterial line insertion
Active Comparator Drug,Placebo Comparator Drug
Norepinephrine 5 mcg IV push,NSS 5 ml IV push
Sponsors
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with age between 18-70 years 2. Patient who undergoes elective surgery with general anesthesia that have indication for arterial line insertion 3. The American Society of Anesthesiologists (ASA) Physical Status Classification I-III
Exclusion criteria
Exclusion criteria: 1. Emergency case 2. Pregnant or lactating female 3. Norepinephrine or sodium metabisulfite or sulfa group allergy 4. Patient with uncontrolled hyperthyroidism or pheochromocytoma 5. Patient with peripheral artery disease or vascular aneurysm or mesenteric ischemia 6. Baseline systolic blood pressure greater than 160 mmHg 7. Patient who continue inotropic drug before arterial line insertion 8. Severe obesity (BMI greater than or equal to 35) 9. Patient with Monoamine oxidase inhibitor (MAOIs) or Tricyclic antidepressant use 10. Patient refusal or withdrawal of intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of attempts Until success arterial line insertion Time | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to success Until success arterial line insertion Sec,Hematoma or Ischemia 24 hours postoperatively Present, Absent | — |
Countries
Thailand
Contacts
Public ContactNaruemol Prachanpanich
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed