The effectiveness of intravenous lidocaine to reduce coughing during laryngeal mask airway insertion

Status

Unknown

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20221207002

Enrollment

Registered

2022-12-07

Start date

2022-10-10

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia with laryngeal mask airway insertion Intravenous lidocaine, Laryngeal mask airway

Interventions

Normal saline same volume as intravenous lidocaine,Intravenous lidocaine 1.5 mg/kg

Placebo Comparator Drug,Active Comparator Drug

Normal saline,Intravenous lidocaine

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients undergo elective surgery under general anesthesia with laryngeal mask insertion

Exclusion criteria

Exclusion criteria: 1.Risk aspiration 2.Protocol drugs allergy 3.Coronary artery disease or arrhythmia 4.Cerebrovascular disease 5.BMI > 30 kg/m2 6.Respiratory tract infection within 2 week 7.Heavy smoking 8.Suspected difficult airway

Design outcomes

Primary

Measure	Time frame
Coughing During LMA insertion Number	—

Secondary

Measure	Time frame
Total propofol During LMA insertion Mean SD or Median (IQR),Movement During LMA insertion Number,Attempt of LMA insertion During LMA insertion Number,Laryngospasm During LMA insertion Number,Gagging During LMA insertion Number,Hiccup During LMA insertion Number,Heart rate Before, 1, 3, 5, 10, 15 after LMA insertion Mean (SD) or median (IQR),Blood pressure Before, 1, 3, 5, 10, 15 after LMA insertion Mean (SD) or median (IQR),Desaturation During LMA insertion Number	—

Measure

Time frame

Total propofol During LMA insertion Mean SD or Median (IQR),Movement During LMA insertion Number,Attempt of LMA insertion During LMA insertion Number,Laryngospasm During LMA insertion Number,Gagging During LMA insertion Number,Hiccup During LMA insertion Number,Heart rate Before, 1, 3, 5, 10, 15 after LMA insertion Mean (SD) or median (IQR),Blood pressure Before, 1, 3, 5, 10, 15 after LMA insertion Mean (SD) or median (IQR),Desaturation During LMA insertion Number

—

Countries

Thailand

Contacts

Public ContactPanida Tapaneeyakorn

Faculty of Medicine, Khon Kaen university

panida_t@kkumail.com0896221237

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026