Outcome of furosemide and oral sodium chloride as alternative treatment for syndrome of inappropriate antidiuresis with fluid restriction failure.

Can furosemide and oral sodium chloride be alternative treatment for syndrome of inappropriate antidiuresis with fluid restriction failure?

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20221205002

Enrollment

Registered

2022-12-05

Start date

2022-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyponatremia from SIADH Failure to fluid restriction treatment SIADH, Fluid restriction, Furosemide, Oral sodium chloride

Interventions

Hyponatremia patients from SIADH who respond to furosemide and oral sodium chloride,Hyponatremia patients from SIADH who did not respond to furosemide and oral sodium chloride

Treatment,Treatment

Responder,Non-responder

Eligibility

Sex/Gender

All

Age

15 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Hyponatremic patients diagnosed with SIADH by Barrter and Schwartz criteria 2. Failure to respond to fluid restriction treatment 3. Age more than 15 years old 4. Asymptomatic hyponatremia

Exclusion criteria

Exclusion criteria: 1. Chronic diuretic therapy 2. Hemodynamic instability 3. Severe hyperglycemia define as blood sugar > 300 mg/dL 4. can not take food by oral or enteral feeding 5. Deny participating in this clinical trial

Design outcomes

Primary

Measure	Time frame
Treatment response rate at 7 days after treatment percent	—

Secondary

Measure	Time frame
factors independently associated with the rise in plasma sodium last serum sodium odd ratio	—

Countries

Thailand

Contacts

Public ContactKittiphan chienwichai

Hatyai hospital

ble_sama@hotmail.com0945946458

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026