non edematous hyponatremia patient Hyponatremia, Urine sodium, Diagnostic accuracy
Conditions
Interventions
Patients with hyponatremia from hypovolemia diagnosed by serum sodium increased and sustained to more than 135 meq/L after normal saline infusion.,Patients with hyponatremia from the syndrome of inapp
Diagnostic,Diagnostic
Hypovoleumic hyponatremia ,SIADH
Sponsors
No sponsor
Eligibility
Sex/Gender
All
Age
15 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Serum sodium <130 meq/L 2. Serum osmolality < 280 mOsm/kg H2O 3. No clinical sign of volume overload (no pulmonary edema, no ascites, no edema) 4. Primary doctor plan to give 0.9%NaCl infusion of at least 500 ml or 3%Nacl infusion of at least 150 ml
Exclusion criteria
Exclusion criteria: 1. Received treatment of hyponatremia ex. NaCl infusion, Diuretics, NaCl tab before 2. Patients with hypothyroid 3. Patients with adrenal insufficiency 4. Patients with chronic diuretic therapy 5. Patients with chronic kidney disease(eGFR<60 ml/min/1.73m2) 5. Cannot collect urine sample in accordance with study protocol 6. known bladder dysfunction or urinary incontinence
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnosis accuracy, Sensitivity and specitivity of urine sodium after normal saline treatment After normal saline infusion 500 ml Percent | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity and specitivity of urine sodium after normal saline infusion 1,000 ml After normal saline infusion 1,000ml Percent,Sensitivity and specitivity of urine osmole after normal saline infusion 1,000 ml After normal saline infusion 1,000ml Percent,Sensitivity and specitivity of urine osmole after normal saline infusion 500 ml After normal saline infusion 500 ml percent | — |
Countries
Thailand
Contacts
Public ContactKittiphan Chienwichai
Hatyai hospital
Outcome results
None listed