Functional outcomes after prophylactic endoscopic carpal tunnel release during volar locking plate fixation of distal radius fracture: a randomized controlled trial

Status

Unknown

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20221130001

Enrollment

Registered

2022-11-30

Start date

2021-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Operative distal radius fracture patients who have indication for volar locking plate fixation Distal radius fracture, endoscopic carpal tunnel release, functional outcome, carpal tunnel syndrome

Interventions

The patients in this group are assigned to perform endoscopic carpal tunnel release after the distal radius fracture fixation with volar locking plate.,The patients in this group are assigned not to p

Experimental Procedure/Surgery,Active Comparator Procedure/Surgery

Prophylactic endoscopic CTR,No prophylactic endoscopic CTR

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Distal radius fracture patients who undergo volar locking plate fixation 2. Aged equal or more than 18 years old

Exclusion criteria

Exclusion criteria: 1. Patients with pre-existing carpal tunnel syndrome 2. Previous carpal tunnel release on the same side of injury 3. Multiple trauma 4. Pathological fracture such as bone tumor, infection 5. Known allergy to acetaminophen, NSAIDs and opioids 6. Unable to communicate or comply to the outcome measurements

Design outcomes

Primary

Measure	Time frame
Patient-rated wrist evaluation (PRWE) 2 weeks, 6 weeks, 3 months, 6 months and 12 months Self-rated questionnaire	—

Secondary

Measure	Time frame
Quick Disabilities of the arm, shoulder, and hand (QuickDASH) 2 weeks, 6 weeks, 3 months, 6 months and 12 months Self-rated questionnaire,Grip strength 2 weeks, 6 weeks, 3 months, 6 months and 12 months Jamar hand grip dynamometer (measured in kilogram),Pain score 2 weeks, 6 weeks, 3 months, 6 months and 12 months Numerical rating scale,Thai version Boston Questionnaire 2 weeks, 6 weeks, 3 months, 6 months and 12 months Self-rated questionnaire,EuroQol- 5 dimensions- 5 levels (EQ-5D-5L) 2 weeks, 6 weeks, 3 months, 6 months and 12 months Quality of life questionnaire,Wrist range of motion 2 weeks, 6 weeks, 3 months, 6 months and 12 months Goniometer,Fingertip to distal palmar crease distance 2 weeks, 6 weeks, 3 months, 6 months and 12 months Fingertip to distal palmar crease distance,Complications 2 weeks, 6 weeks, 3 months, 6 months and 12 months Surgical site infection, wound dehiscence, median nerve palsy, palmar cutaneous nerve palsy, complex regional pain syndrome	—

Measure

Time frame

Quick Disabilities of the arm, shoulder, and hand (QuickDASH) 2 weeks, 6 weeks, 3 months, 6 months and 12 months Self-rated questionnaire,Grip strength 2 weeks, 6 weeks, 3 months, 6 months and 12 months Jamar hand grip dynamometer (measured in kilogram),Pain score 2 weeks, 6 weeks, 3 months, 6 months and 12 months Numerical rating scale,Thai version Boston Questionnaire 2 weeks, 6 weeks, 3 months, 6 months and 12 months Self-rated questionnaire,EuroQol- 5 dimensions- 5 levels (EQ-5D-5L) 2 weeks, 6 weeks, 3 months, 6 months and 12 months Quality of life questionnaire,Wrist range of motion 2 weeks, 6 weeks, 3 months, 6 months and 12 months Goniometer,Fingertip to distal palmar crease distance 2 weeks, 6 weeks, 3 months, 6 months and 12 months Fingertip to distal palmar crease distance,Complications 2 weeks, 6 weeks, 3 months, 6 months and 12 months Surgical site infection, wound dehiscence, median nerve palsy, palmar cutaneous nerve palsy, complex regional pain syndrome

—

Countries

Thailand

Contacts

Public ContactPanai Laohaprasitiporn

Faculty of Medicine Siriraj Hospital, Mahidol University

panai.lao@mahidol.ac.th0865678565

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026