Healthy with ASA (American association of Anesthesiologists) class 1 and class 2 0.5% Chitosan, Mouth spray, Antimicrobial activity, Safety
Conditions
Interventions
Mouth spray with 0.5% Chitosan ,Mouth spray without Chitosan ,0.12% Chlorhexidine gluconate (Mybacin)
0.5% Chitosan mouth spray ,Mouth spray without Chitosan ,Chlorhexidine mouth spray
Sponsors
Faculty of Dentistry, Khon Kaen University
Eligibility
Sex/Gender
All
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. ASA (American association of Anesthesiologists) class 1 and class 2 2. at least 10 teeth in the mouth
Exclusion criteria
Exclusion criteria: 1. Chitosan allergy 2. Preservatives or flavoring agents for allergy 3. High-risk caries 4. Gingival bleeding index of more than 15% 5. Dental crowns or bridges 6. Pathologic oral lesion 7. Received antibiotics, steroids, or immunosuppressants within the last 3 months 8. Pregnant or breastfeeding 9. Alcohol consumption 10. Smoking, marijuana, or other drugs 11. Listening, speaking, reading, and writing in Thai
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antimicrobial activity at baseline, day 1 and day 14 end of the intervention Microbial culture | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety at baseline, day 1 and day 14 end of the intervention Clinical assessment, sialometry and questionnaire | — |
Countries
Thailand
Contacts
Public ContactWilairat Sarideechaigul
Faculty of Dentistry, Khon Kaen University
Outcome results
None listed