Scalp nerve block, Supratentorial craniotomy, Hemodynamic response, Postoperative analgesia, Levobupivacaine, Nalbuphine Scalp nerve block, Supratentorial craniotomy, Hemodynamic response, Postoperative analgesia, Levobupivacaine, Nalbuphine
Conditions
Interventions
scalp nerves block with 0.25% levobupivacaine with 10 mg of nalbuphine in 1:200,000 adrenaline total 20 mL,scalp nerves block with 0.25% levobupivacaine in 1:200,000 adrenaline total 20 mL
Experimental Drug,Placebo Comparator Other
NB group,CB group
Sponsors
Department of anesthesiology, King chulalongkorn Memorial hospital
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 20 to 65 year-olds ASA Physical Status I and II Undergoing elective supratentorial craniotomy for the first time
Exclusion criteria
Exclusion criteria: Allergic to levobupivacaine, nalbuphine Infection at the block site/ Scalp Infection Preoperative Glasgow Coma Scale (GCS) < 15 Inability to measure pain intensity by verbal numeric rating scale (NRS) Inability to use PCA
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of postoperative analgesia between groups 24 hour post operative Time to first rescue fentanyl | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative hemodynamic responses intraoperative and post operative first 24 hour Mean arterial pressure(MAP), Heart rate(HR),Overall pain score over the first 24 postoperative hour post operative first 24 hour Numaric rating scale(NRS),Incidence of side effects post operative first 24 hour PONV score, glasgow coma score(GCS) | — |
Countries
Thailand
Contacts
Public ContactKornkamon Yuwapattanawong
Faculty of medicine ,King Chulalongkorn Memorial hospital
Outcome results
None listed