The patients undergoing cesarean section had incidented of hypotension after spinal anesthesia. hypotension, anesthesia, spinal, cesarean section, fluid gelatin, phenylephrine.
Conditions
Interventions
The study was conducted on the basis of randomized comparative trial, therapy (intervention) in female patients aged 18-44 years, 37-40 weeks gestational age, during 2020-2021 at Chaiyaphum hospital,
Active Comparator Drug,Experimental Drug
Preloading by only Fluid gelatin,Preloading by fluid gelatin and intravenous phenylephrine during spinal anesthesia
Sponsors
Chaiyaphum hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 44 Years
Inclusion criteria
Inclusion criteria: 1. Pregnancy undergoing to ceasarean section and GA 37-40 wk 2. Spinal anesthesia
Exclusion criteria
Exclusion criteria: 1. complication of obstetric condition, risk bleed over 1000 mL 2. PIH, HT, renal failure, CHF, heart disease, arrhythmia, DM, coagulopathy or thrombocytopenia, asthma, OSA, thyroid disease, liver disease, use MAOI, other drugs that prolonged heart conduction 3. Abnormal of fetus 3. Postural hypotension un-correct 4. Body weight less than 50 kg or more than 80 kg, BMI over 35 kg/m2 5. BP over 140/90 mmHg, SBP less than 90 mmHg, HR less than 60 /min 6. Sensitivity to phenylephrine or fluid gelatin 7. Deny to study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hypotension after spinal anesthesia to end of surgery After spinal block to end of surgery mesure the vital signs | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of Hypotension event and Complication after spinal block After spinal block to end of surgery mesure the vital signs, observe the signs and symptomps | — |
Countries
Thailand
Contacts
Public ContactBundharika Artnasiaw
Chaiyaphum Hospital
Outcome results
None listed