Strongyloidiasis in patients who administered high-dose corticosteroids. S. stercoralis, strongyloidiasis, ivermectin, prophylaxis, corticosteroids
Conditions
Interventions
Those who received 200 mcg/kg/day of ivermectin for two consecutive days before starting high-dose corticosteroids even if the results of stool test(s) for S. stercoralis were negative or nonexistent.
Prevention,Prevention
Universal prophylaxis,Definite therapy
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 18 years of age or older Admitted to Khon Kaen University Srinagarind Hospital between January 2015 and June 2019 Received at least 0.5 mg/kg/day of prednisolone or equivalent for at least 14 consecutive days
Exclusion criteria
Exclusion criteria: Had received ivermectin or other drugs for S. stercoralis such as albendazole within 30 days before enrollment Had evidence of strongyloidiasis but did not receive treatment within seven days Allergic to ivermectin Medical records were missing important information
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of S. stercoralis cases detected at 12 months after high dose steroid initiation Fecal examination | — |
Secondary
| Measure | Time frame |
|---|---|
| Cost at 12 months after high dose steroid initiation Thai Baht | — |
Countries
Thailand
Contacts
Public ContactWantin Sribenjalux
Faculty of Medicine, Khon Kaen University
Outcome results
None listed