Upper GI cancer , cancer screening and work-up for symptomatic patients in patients with dysphagia, dyspepsia, reflux, abdominal pain, or anemia Simethicone , N-acetylcysteine , lidocaine , ice popsicle, topical pharyngeal anesthesia unsedated esophagogastroduodenoscopy, unsedated upper gastrointestinal endoscopy
Conditions
Interventions
-6 ml viscous lidocaine solution ( 20 mg/ml ) with pre-medication agents (Simethicone 80 mg
+ NAC 600 mg) premixed in ice popsicle formula
-Formed solution of viscous lidocaine , simethicone 80 mg an
Experimental Drug,Experimental Drug
Lidocaine with pre-medication agents in ice popsicle formula group ,Lidocaine ice popsicle formula Then applied pre-medication solution via EGD port group
Sponsors
Faculty of medicine ,Thammasat university hospital
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: A minimum age of 20 years Eligible for unsedated diagnostic EGD via the oral route by pharyngeal anesthesia at Thammasat University Hospital Upper GI cancer , cancer screening and work-up for symptomatic patients in patients with dysphagia, dyspepsia, reflux, abdominal pain, or anemia Patients who did not have allergy and contraindications to pre-medications with a compound solution ( simethicone , N-acetylcysteine and lidocaine ) All patients were fully informed of the purpose of this study and consent was obtained from all participants before this study
Exclusion criteria
Exclusion criteria: Previous upper gastrointestinal surgery Severe dysphagia ( Dysphagia grade V,VI ) Clinical obstruction Corrosive ingestion Upper gastrointestinal bleeding Pregnancy Contraindication for EGD Allergy to pre-medications Emergency cases and unstable vital signs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visualisation After intervention was done Total visibility score | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of water used to allow suitable visualization of gastric mucosa After intervention Volume of water,Time to complete the EGD After intervention Minutes,Safety outcome During intervention Oxygen saturation , Heart rate , Blood pressure ,Endoscopist satisfication After intervention Satisfaction score,Patient satisfication After intervention Satisfaction score | — |
Countries
Thailand
Contacts
Public ContactPailin Intarasangkhanawin
Thammasat university hospital
Outcome results
None listed