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Prevalence, Risk Factors and Clinical Outcomes of Sepsis Induced Myocardial Dysfunction (SIMD): A Prospective Study in King Chulalongkorn Memorial Hospital, Thailand

Prevalence, Risk Factors and Clinical Outcomes of Sepsis Induced Myocardial Dysfunction (SIMD): A Prospective Study in King Chulalongkorn Memorial Hospital, Thailand

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20221112004
Enrollment
72
Registered
2022-11-12
Start date
2022-09-27
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis induced myocardial dysfunction Sepsis induced myocardial dysfunction, septic shock, sepsis, echocardiogram

Interventions

KCMH sepsis patients without sepsis induced myocardial dysfunction (SIMD) who were admitted to an intensive care unit (ICU) between 2021-2022, aged 20-100 years: sepsis patients without SIMD,KCMH seps
Other,Other
Controlled group,Compared group

Sponsors

Faculty of Medicine, Chulalongkorn university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 100 Years

Inclusion criteria

Inclusion criteria: Compared group 1. Admitted patients who were diagnosed as sepsis (sepsis, severe sepsis, septic shock) 2. Sepsis patients who were diagnosed as sepsis induced myocardial dysfunction 3. Aged 20-100 years during sepsis Controlled group 1. Admitted patients who were diagnosed as sepsis (sepsis, severe sepsis, septic shock) 2. Aged 20-100 years during sepsis

Exclusion criteria

Exclusion criteria: 1. Not fulfill criteria of sepsis from Sepsis-3 definition 2. Prior history of reduced left ventricular ejection fraction (< 40%) 3. Concurrent acute myocardial infarction 4. Echocardiogram shows stress induced cardiomyopathy 5. History of prior medications or drugs which can cause myocardial dysfunction such as doxorubicin, trastuzumab, amphetamine 6. Cardiac arrest in admission

Design outcomes

Primary

MeasureTime frame
Prevalence of SIMD At time of recruitment Percentage

Secondary

MeasureTime frame
Risk factors At time of recruitment Odd ratio,Clinical outcome; 28-day mortality 28 days after recruitment Odd ratio

Countries

Thailand

Contacts

Public ContactWissarut Sakulpaptong

Faculty of Medicine, Chulalongkorn university

w.sakulpaptong@gmail.com0870404808

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026