more than 18-year intubated patient in intensive care unit who required intravenous anesthetic drug and fentanyl. intubated patient, opioid consumption, pain assessment, analgesia Nociception Index, ANI, sedation in intensive care unit
Conditions
Interventions
ANI guided fentanyl administration for pain controlled ,standard of care followed Ramathibodi sedation protocol
Experimental Device,No Intervention No treatment
ANI ,standard of care
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. More than 18-year intubated patient admitted to intensive care unit with. 2. Required intravenous anesthetic drug and fentanyl for sedate. 3. Accept to participate in the research project and sign a letter of consent to participate in the research project.
Exclusion criteria
Exclusion criteria: 1. Patient with unstable hemodynamic requiring high dose of vasopressor 2. Patient with cardiac arrythmia 3. Patient with chronic opioid used 4. Patient with autonomic dysfunction 5. Patient with allergic to study drug 6. Patient refuse to participate in research projects or withdraw from research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fentanyl consumption at 48 h at 48 h after enrollment ANI | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of pain measurement at 4,8,12,16,20,24,28,32,36.40,44 and 48 h after enrolled ANI and BPS score,Association of side effects from the use of analgesics with the amount of analgesics used. ICU stayed CAM-ICU, withdrawal symptom | — |
Countries
Thailand
Contacts
Public Contactchutima plukmonton
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed