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Prevalence and clinicopathological characteristics of programmed death-ligand 1 expression in Thai patients with gastric cancer

Prevalence and clinicopathological characteristics of programmed death-ligand 1 expression in Thai patients with gastric cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20221031001
Enrollment
250
Registered
2022-10-31
Start date
2018-10-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The primary objective is to investigate the correlation between PD-L1 expression and gastric cancer staging according to American Joint Committee on Cancer (AJCC) TNM staging, eighth edition. The secondary objectives are to investigate the correlation between PD-L1 expression and other clinicopathological characteristics and overall survival. PD-L1 expression, gastric cancer, clinicopathological characters, combined positive score, overall survival

Interventions

Patients with gastric cancer and PD-L1 expression
Other
Gastric cancer patients

Sponsors

Faculty of Medicine, Chiang Mai University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Tissue samples from patients who had newly diagnosed gastric cancer and underwent either biopsy or surgical treatment in the Maharaj Nakorn Chiang Mai hospital from January 1, 2018, to December 31, 2021 2. Age more than 18 years old. 3. Tissue sample was available to assess PD-L1 expression by immunohistochemistry technique.

Exclusion criteria

Exclusion criteria: 1. No recorded hospital admission or follow-up data in Maharaj Nakorn Chiang Mai hospital electronic medical record. 2. Diagnosed other types of malignancy (Gastrointestinal stromal tumor, Lymphoma, Neuroendocrine tumor, or Metastatic tumor). 3. Have other active malignancies or during chemotherapy or radiation for other malignancies.

Design outcomes

Primary

MeasureTime frame
PD-L1 expression At the beginning of study combined positive score

Secondary

MeasureTime frame
PD-L1 expression 0, 12, 24, 36, 48, 60, 72, 84 months overall survival

Countries

Thailand

Contacts

Public ContactTaned Chitapanarux

Faculty of Medicine, Chiang Mai University

thaitaned@yahoo.com660896379966

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026