Platelet dysfunctions, endothelial dysfunction, and high blood pressure in healthy adults and hypertensive patients. thromboembolism, hypertension, healthy population and patients with hypertension
Conditions
Interventions
Moringa oleifera leaves in capsule 900 mg oral,Placebo intake
Moringa oleifera leaves,Placebo
Sponsors
Faculty of Medicine Ramathibodi Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 59 Years
Inclusion criteria
Inclusion criteria: 1. age 40-59 years 2. Systolic blood pressure < 140 mmHg and diastolic blood pressure < 90 mmHg for healthy population group 3. Systolic blood pressure 140-159 mmHg and diastolic blood pressure 90-99 mmHg for hypertensive group
Exclusion criteria
Exclusion criteria: 1. smoking 2. pregnancy 3. medication or herbal use that affects platelet function 4. medical conditions or underlying diseases that affects platelet function 5. underlying diseases: cardiovascular diseases, chronic lung diseases, chronic liver diseases, chronic kidney diseases, and cancer, etc. 6. participants' voluntary withdrawal of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet aggregation within 4 hours Flow cytometry | — |
Secondary
| Measure | Time frame |
|---|---|
| endothelial function within 4 hours chemiluminescence | — |
Countries
Thailand
Contacts
Public ContactKulapong Jayanama
Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed