Infant gut microbiome microbiome, gut, infant, cesarean, vaginal delivery
Conditions
Interventions
Infants delivered by vaginal delivery,Infants delivered by cesarean delivery
Basic Science,Basic Science
Vaginal delivery,Cesarean delivery
Sponsors
Strategic Wisdom and Research Institute, Srinakharinwirot University
Fundamental Fund, National Research and Innovation Information System
Eligibility
Sex/Gender
All
Age
No minimum to 48 Hours
Inclusion criteria
Inclusion criteria: 1. Term healthy newborn with normal vital signs and physical examination. 2. Delivered at HRH Maha Chakri Sirindhorn Medical Center, Faculty of Medicine, Srinakharinwirot University, Thaialnd. 3. Delivered from pregnant women with no infection history. 4. Delivered from pregnant women not received antibiotic treatment except for Cesarean empirical antibiotic prophylaxis.
Exclusion criteria
Exclusion criteria: 1. Infant's fecal specimen cannot be corrected within 48 hours after delivery 2. Infant diagnosed with gastrointestinal abnormalities, other structural abnormalities or genetic disease after delivery. 3. Infant diagnosed with complications after delivery e.g., jaundice that need phototherapy or exchanged transfusion, early neonatal sepsis 4. Infant received antibiotic within 48-72 hours after delivery before collecting the fecal specimen.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alpha diversity After complete sample collection QIMME,Difference of gut microbiomes After complete sample collection Non-parametric t-test | — |
Secondary
| Measure | Time frame |
|---|---|
| Gravida 1 year Record form,Parity 1 year Record form,Abortion 1 year Record form,Gestational age 1 year Record form,Ethnic 1 year Record form,Income 1 year Record form,Religion 1 year Record form,BMI 1 year Record form,ANC risk 1 year Record form,Medications 1 years Record form,Underlying disease 1 year Record form,Route of delivery 1 year Record form,Intrapartum complications 1 year Record form,Postpartum complications 1 year Record form,Infant sex 1 year Record form,Birth body weight 1 year Record form,APGAR score 1 year Record form | — |
Countries
Thailand
Contacts
Public ContactNichapat Pahirah
Faculty of Medicine, Srinakharinwirot University
Outcome results
None listed