Cleft palate Cleft palate surgery , ketamine, paediatric, postoperative pain
Conditions
Interventions
Ketamine 0.5 mg/kg IV bolus pre-incision,intravenous NSS
Active Comparator Drug,Placebo Comparator No treatment
Ketamine 0.5 mg/kg IV bolus pre-incision,NSS
Sponsors
Khon Kaen University
Eligibility
Sex/Gender
All
Age
9 Months to 6 Years
Inclusion criteria
Inclusion criteria: Children age of 9 months to 6 years, ASA I to II, Undergoing elective palatoplasty and palatoplasty with other surgery e.g., cheiloplasty, myringotomy, etc.
Exclusion criteria
Exclusion criteria: Parents refusal, Children with mental retardation, Patient with contraindication of ketamine e.g., uncontrolled hypertension, increase intracranial pressure, increase intraocular pressure, etc., History of allergy to any of the study drugs, Chronic pain syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score 0,15,30,45,60 minute post-operative FLACC scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic effect of ketamine 0,5,10,15,30 minute after drudged administration BP, HR, MAP,Time to first analgesic requirement in PACU minutes,Total analgesic consumption at PACU in PACU Total fentanyl administration in mcg IV,Emergence time time after discontinuation of anesthesia to successful extubation minute,Incidence of emergence delirium in PACU PAED score,Incidence of postoperative nausea and vomitting (PONV) in PACU dry heaves, nausea, vomitting,Parent's satisfaction in PACU rating score of 0-10 | — |
Countries
Thailand
Contacts
Public ContactBusapun Sermdumrongsak
Faculty of Medicine, Khon Kaen University
Outcome results
None listed